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14 Thursday, April 16, 2015 EW SHOW DAILY paper in their meeting tote bag upon registration. EW References 1. Weiss JS, Møller HU, Aldave AJ, Seitz B, Bredrup C, Kivelä T, Munier FL, Rapuano CJ, Nischal KK, Kim EK, Sutphin J, Busin M, Labbé A, Kenyon KR, Kinoshita S, Lisch W. IC3D classification of corneal dystrophies— edition 2. Cornea. 2015 Feb;34(2):117–59. 2. Gomes JA, Tan D, Rapuano CJ, Belin MW, Ambrósio R Jr., Guell JL, Malecaze F, Nishida K, Sangwan VS; Group of Panelists for the Global Delphi Panel of Keratoconus and Ectatic Diseases. Global consensus on kera- toconus and ectatic diseases. Cornea. 2015 Apr;34(4):359–69. other international corneal societies (the Asia Cornea Society, EuCornea, and PanCornea), gathered a panel of 36 experts to create a guide for navigating the myriad of diagnoses and treatment options. Using the Delphi method, which consists of several rounds of structured questioning, panelists reached a consensus on the defini- tions of ectatic diseases and the best medical and surgical treatments. The paper's authors created a flow- chart showing a logical sequence of treatment options for a patient with keratoconus, allowing practitioners to visualize the available choices and help them decide when to move on to the next step. World Cornea Congress VII attendees will receive a copy of the corneal anatomy—epithelial and subepithelial dystrophies; epithelial- stromal dystrophies caused by mu- tations in the transforming growth factor, beta-induced gene (TGFBI); stromal dystrophies; and endothelial dystrophies. One superior feature of the new classification system is the grouping of the TGFBI dystrophies. Dystro- phies in this group affect multiple layers of the cornea, so they were grouped differently in the past, de- spite the fact that they are caused by mutations in the same gene. Templates for each dystrophy in the new IC3D edition now include inheritance patterns and gene involvement in addition to clinical signs and symptoms. New electron micrographs and histopathology images are also included to comple- ment the traditional clinical photo- graphs. Jayne S. Weiss, MD, New Or- leans, the study's lead author, will present the new classification system today at 7:30 a.m., in the "Dystro- phies, Degenerations, and Genetics" session. Recommendations for managing ectasia With input from experts around the world, "Global Consensus on Keratoconus and Ectatic Diseases" provides recommendations for de- fining and treating keratoconus and other ectactic disorders. Advanced corneal measurement devices—specifically, topography and tomography—have allowed ophthalmologists to identify ectasia much earlier than was previous- ly possible. As a result, they have found the prevalence of keratoco- nus in the general population to be greater than assumed. With a deepening knowledge of corneal mechanics and more surgical options than ever before, physicians often disagree about the definitions of ectactic disorders and what should be the best course of action for treatment. For this paper, the Cornea Society, along with the 3 Specialists present a reclassification of corneal dystrophies and recommendations for treating keratoconus T he Cornea Society recently published 2 papers in the journal Cornea that provide ophthalmologists with tools to better diagnose and treat 2 major groups of corneal diseases: corneal dystrophies and ec- tatic disorders. "IC3D Classification of Corneal Dystrophies—Edition 2," published in February 2015, and "Global Consensus on Keratoconus and Ectatic Diseases," published in April 2015, offer diagnosis and treatment guidelines that both cor- nea specialists and comprehensive ophthalmologists can use in their practice today. Redefining corneal dystrophies "IC3D Classification of Corneal Dystrophies—Edition 2" is a revised version of the International Clas- sification of Corneal Dystrophies (IC3D) system published in 2008. Classifying corneal dystrophies has been challenging in the past, as many were described purely on clinical presentation, and the genet- ic basis of these diseases remained unknown. But with the devel- opment of DNA sequencing and improved histology and microscopy techniques, cornea specialists have been able to better understand their genetic and cellular origins. The 2008 system classified cor- neal dystrophies based on the affect- ed corneal layer. The IC3D consisted of templates for each disease that included clinical, pathological, and genetic information as well as repre- sentative clinical photographs. Authors of IC3D Edition 2 updated the classification system to include the major clinical, histo- pathologic, and genetic information that has been learned in the past 7 years. They reclassified the corneal dystrophies into 4 groups based on by Lauren Lipuma EyeWorld Staff Writer Cornea Society publishes guides for managing corneal diseases

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