Eyeworld Daily News

EW SHOW DAILY 32 ASCRS News Today Saturday, May 7, 2016 experience with students, residents, and fellows. Dr. Grant was the recipient of numerous honors and awards, including the Proctor Medal (Asso- ciation for Vision and Research in Ophthalmology), the Knapp Medal (American Medical Association), and the Howe Medal (American Oph- thalmological Society). Dr. Grant died in November 2001 at the age of 86. Alan B. Scott, MD Alan B. Scott, MD, has practiced adult and pediatric ophthalmol- ogy for more than 50 years but is perhaps best known for his ground- breaking work in developing and manufacturing botulinum toxin type A (now known as Botox) for therapeutic use in eye muscles. Dr. Scott was the first to use an inject- able form of the neurotoxin as a treatment for strabismus. Today, the drug—derived from Clostridium bot- ulinum—is used around the world to treat myriad medical and cosmetic conditions. In the 1960s, as a senior sci- entist at the Smith-Kettlewell Eye Research Institute in San Francisco, Dr. Scott began injecting botulinum toxin type A into the extraocular muscles of monkeys with the hope that its muscle-relaxing properties would provide an alternative to surgery when treating strabismus. Encouraged by the results, he ap- plied for and received approval from Dr. Grant's other major work developed from his collabo- ration with long-time friend and Howe Laboratory colleague Paul Chandler, MD. Their collective clin- ical observations and definitive ideas on treating glaucoma were shared in a lecture series that later became Lectures on Glaucoma. First published in 1965, Lectures on Glaucoma is one of the field's seminal texts on the medical practice and surgical man- agement of glaucoma and has been counted among the most influential of the 20th century. Generations of ophthalmologists have found the book to be an invaluable reference. In 1986, the book—revised and up- dated by David Epstein, MD—was published as Chandler and Grant's Glaucoma. Now in its fifth edition, Chandler and Grant's Glaucoma con- tains the well-established fundamen- tals offered by Drs. Grant and Chandler, from the mechanisms behind clinical observation to de- tails on treating individual patients in the office, as well as the added experience of world-class glaucoma experts trained from the original teachings of the book. Dr. Grant served as the first di- rector of the glaucoma consultation service at MEEI and remained in the position until 1982. In 1974, he became the first David Glendenning Cogan professor of ophthalmology at Harvard Medical School. He was a devoted teacher who always took the time to share his knowledge and of tonography, which made the assessment of aqueous outflow a clinically relevant and useful test. He concluded that in glaucoma patients, the facility of aqueous out- flow was decreased, indicating the trabecular meshwork was plugged. Tonography helps assess the risk of developing glaucoma and is still use- ful when studying the mechanism of action of medications. Dr. Grant attended Harvard College as an undergraduate and went on to graduate from Harvard Medical School in 1940. While there, he had his first taste of oph- thalmic research while studying ophthalmology in elective courses. Following medical school, he accept- ed a surgical internship at the Henry Ford Hospital in Detroit, where he stayed for 1 year. In 1943, Dr. Grant started his career at the Howe Labo- ratory at Massachusetts Eye and Ear Infirmary (MEEI). With World War II in full swing, the need to treat eye injuries sustained by chemicals was a priority, and Dr. Grant worked closely with David Cogan, MD, on the effects of mustard gas on the eye. Under the direction of Dr. Cogan, he gained valuable knowl- edge in toxicology and biochemistry. Dr. Grant's work in the laboratory, and his lifelong interest in organ- ic chemistry, resulted in the 1962 publication of his first book, Toxicol- ogy of the Eye. He would produce 4 editions of the book. Two preeminent ophthalmic leaders will be inducted into the ASCRS Hall of Fame at today's ASCRS Opening General Session W. Morton Grant, MD W. Morton Grant, MD—a re- nowned ophthalmic clinician-sci- entist and educator—was by all accounts a quiet and humble man despite being a world leader in the study and treatment of glaucoma. Dr. Grant's many contributions to the field include his development ASCRS Hall of Fame inducts Drs. Grant and Scott W. Morton Grant, MD Alan B. Scott, MD ASCRS Hall of Fame members through 2015 1999 José Barraquer, MD Ramon Castroviejo, MD Stewart Duke-Elder, FRS J. Donald Gass, MD Charles Kelman, MD A. Edward Maumenee, MD Marshall Parks, MD Harold Ridley, FRS Charles Schepens, MD Lorenz Zimmerman, MD 2000 Ernst Fuchs, MD Hans Goldmann, MD Albrecht von Graefe, MD Robert Machemer, MD Frank Walsh, MD 2001 Cornelius Binkhorst, MD David Cogan, MD Svyatoslav Fyodorov, MD Hermann von Helmholtz, MD Gerd Meyer-Schwickerath, MD 2002 Bernard Becker, MD Jules Gonin, MD Edward W.D. Norton, MD Arnall Patz, MD 2003 Danièle Aron-Rosa, MD Joaquin Barraquer, MD Paul Chandler, MD William Hoyt, MD Norman Jaffe, MD Jules Stein, MD 2004 Claes Dohlman, MD, PhD Jonas Friedenwald, MD Govindappa Venkataswamy, MD 2005 Jules François, MD, PhD Gholam Peyman, MD Robert Sinskey, MD 2006 Algernon Reese, MD 2007 David Apple, MD Dame Ida Caroline Mann, FRCS 2008 Allvar Gullstrand, MD Stephen Trokel, MD 2009 Jacques Daviel, MD Endre Balazs, MD 2010 Judah Folkman, MD Alan Bird, MD 2011 Frederick Verhoeff, MD Alfred Sommer, MD 2012 Louis Braille Jack Holladay, MD 2013 Saiichi Mishima, MD Richard Kratz, MD 2014 Vladimir Filatov, MD Theo Seiler, MD, PhD 2015 Gunter von Noorden, MD Frederick Blodi, MD

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