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EW SHOW DAILY 2 Wednesday, April 18, 2018 "Glaucoma is firing on all cylin- ders," Dr. Radcliffe said. The final papers presented in the refractive category were shared by Blake Williamson, MD, Baton Rouge, Louisiana. The first paper he presented was "More Eyes with 20/10 Distance Visual Acuity At 12 Months Versus 3 Months In A Topography-Guided Excimer Laser Trial: Possible Con- tributing Factors." A conclusion from the study was that the number of eyes with BCVA of 20/10 was 20 times great- er at 12 months versus preop after receiving topography-guided LASIK treatment. Dr. Williamson noted that the paper indicated that this increase may be due to a decrease in corneal higher order aberrations, treatment centered on the corneal apex vs. the center of the pupil, and epithelial remodeling. He noted that a retrospective, multicenter clinical trial of topography is underway with 11 investigative sites to further eval- uate full data sets. The other papers he presented were "Clinical Outcomes and Vector Analysis in Myopia Patients with High Astigmatism with Small-In- cision Lenticule Extraction and Corneal Wavefront-Guided Transep- ithelial PRK" and "Contralateral Eye Comparison of Quality of Vision in Wavefront-Guided and Wavefront- Optimized LASIK." During the panel discussion, Dr. Thompson said that "to be a comprehensive refractive surgeon, it amazes me the technology that it takes." The first study "was a wonderful study to guide all of us trying to do better topo-guided," he said. EW Editors' note: The physicians have financial interests with various ophthalmic companies. keratoconus in terms of preventing steepening and further thinning of the cornea, as proof of "the deeper the better" concept. Femtosecond laser-assisted crosslinked corneas clinically remained stable with no progression after 2 years. He also presented papers on "Bowman Layer Graft Surgery for Keratoconus" and "Effect of Cornea Preservation Time on Descemet Stripping Automated Endothelial Keratoplasty Success and Endothelial Cell Loss: A Multi-Center Random- ized Clinical Trial Cornea Preserva- tion Time Study." During the panel discussion, Dr. Holland said that he found femto- second crosslinking to be an aggres- sive approach but also noted that "if you don't stop progression of ectasia, [patients] will need kerato- plasty." He thinks that a technique that can make penetration deeper is worthwhile. Dr. Donnenfeld noted that he has some concerns with the method to get the riboflavin deeper in the cornea and said it's important to ensure you're not damaging the cor- nea when attempting to get deeper penetration. Next, Nathan Radcliffe, MD, New York, presented the best glauco- ma papers, first highlighting "Evalu- ation of Ab Interno Subconjunctival Drainage Device in the Management of Glaucoma: Nine-Month Results." In a trial of the XEN Gel Stent (Aller- gan, Dublin, Ireland), results showed excellent intraocular pressure reduc- tion (36% at 9 months) and reduc- tion in medications, Dr. Radcliffe said, and all side effects were single digit. Other papers he presented on included: "Outcomes of Ab Inter- no Gel Stent Placement With and Without Previous Incisional Glau- coma Procedures," "Stanniocalcin-1 is an Ocular Hypotensive Agent and a Downstream Effector Molecule That is Necessary for the Intraocular Pressure-Lowering Effects of Latano- prost," and "Outflow Facility Effects of Three Schlemm's Canal MIGS Devices." Prevent Negative Dysphotopsia" and "Optical Quality Assessment of Intraocular Lenses with Localized Opacification Associated with the Intraocular Injection of Gas." Sharing some of the best cornea papers was John Hovanesian, MD, Laguna Hills, California. The first paper he presented was "Femtosecond-Assisted Crosslink- ing vs. Conventional Crosslinking: Proof of Concept of the Deeper the Better." This sought to compare fem- tosecond laser-assisted crosslinking outcomes with conventional proce- dures and to prove the concept that deeper stromal crosslinking better dampens the progression of ectasias. The paper concluded that cross- linking of the posterior corneal stro- ma deeper than 250 microns could be achieved with femtosecond la- ser-assisted crosslinking better than any other conventional procedures, favoring an effective stabilization of improving post-refractive second eye IOL calculations. Following Dr. Tipperman, Oliver Findl, MD, Vienna, Austria, presented several of his selected cataract papers. The first paper he discussed was "Implantation of Scharioth Macular Lens in AMD: Results of a European Multicenter Clinical Trial." The idea here, he said, is the new technology would have sufficient magnification, is an easy and safe surgery, is inde- pendent from the lens status, has no reductions of the visual field, is not affecting distance vision, is revers- ible, and is affordable. From the study, paper authors concluded that the SML seems to increase near vision without affect- ing distance vision. Patient selection is key, and some postoperative visual training is needed. The other papers he discussed were "Modified IOL Design to The Best continued from page 1 Dr. Hovanesian shares some of the best cornea papers from the meeting. TRANSFORMING O P H T H A L M I C C A R E W I T H SUSTAINED RELEASE THERAPIES VISIT US AT BOOTH #1610 PP-US-OTX-0016 © 2018 Ocular Therapeutix, Inc. All rights reserved.

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